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Real-world data · Clinical trials · Health education

Intelligence appliedto the health oflarge populations.

From the community health worker's home visit to scientific evidence: we turn Brazilian primary care into data that cares.

12.4 Bprimary care records
184 Mactive patients
27Brazilian states
41.9%of records are home visits

Source: medRxiv, 2026.

Published and presented in

JAMA CardiologyThe Lancet Regional Health – AmericasAmerican Heart Association — StrokeAmerican College of CardiologyUniversity of CambridgeEuropean Society of CardiologyISPOR — Value in HealthmedRxivClinicalTrials.gov
Primary care in data

Primary care like you've never seen it

Far from “basic”: primary care is the front door of Brazil’s public health system (SUS) and one of the largest national health information systems in the world.

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12.4 billionprimary care records
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184 millionactive patients
✓
27 statesall of Brazil in the database

Nationwide scale

Since 2013, every Family Health team in Brazil has recorded care in the same standard: a foundation for real-world evidence.

Digital care pathwaysActive
ChronicHypertension · Diabetes
CardiovascularStroke · Heart failure
RespiratoryCOPD
RareRare diseases

From chronic to rare

Digital care pathways follow each condition closely, from hypertension to rare diseases, while patients stay in their community.

ACS
Home visits41.9% of all records
UBS
Procedures35.9% of records in 2025
+
Individual and dental careAt the family health unit

The front door of the system

Care starts at the primary care unit and in families’ homes, long before the hospital.

37×

Growth in 11 years

From 53.3 million records in 2014 to 1.96 billion in 2025.

RuralAmazonUrban outskirts

Who research usually leaves out

Rural, Amazonian and peri-urban populations, historically underrepresented in biomedical research.

JAMA CardiologyThe Lancet RHStroke

Data that becomes science

Results published in international journals.

Source: medRxiv, 2026.

CRITICAL INFRASTRUCTURE

The bridge between primary care and global science.

We turn everyday care into reliable evidence, with security and governance, and bring the results back to the community.

From the field to evidence

Data is born at every home visit

  1. 01Home visit

    The community health worker records the visit on a tablet, in each family's home.

    Community health worker records the visit on a tablet
  2. 02Qualified registries

    Municipal databases corrected and updated with digital support, with no rework.

    Tablet running the epHealth app
  3. 03Monitored care

    Hypertension and diabetes closely monitored, including at home.

    Woman measuring her blood pressure at home
  4. 04Evidence

    Real-world data that becomes studies, publications and health decisions.

    Team analyzing data dashboards on monitors
Community health worker records the visit on a tablet Tablet running the epHealth app Woman measuring her blood pressure at home Team analyzing data dashboards on monitors
In the field
Real Brazil

From the semi-arid backlands to riverside communities

Wherever public health happens, technology needs to get there. Real photos of teams in the field.

Community health worker on a motorcycle on the way to a visit
On the way to a visit
Team arriving by boat at a riverside community
Riverside communities
Community health worker beside a resident at her front door
A bond with every family
Mud-brick house in the semi-arid backlands
Semi-arid backlands
Community health workers in a training session
Health worker training
Studies

Ethical science, careful data

Registered on ClinicalTrials.gov and approved by Brazil's research ethics system.

NCT07846319Coming soon

ARISE

45,000planned participants

Prediabetes and type 2 diabetes screening in primary care. Implementation study.

View on ClinicalTrials.gov
NCT07361276Recruiting

CLEAR-HTN

15,000planned participants

Hypertension treatment patterns in public primary care. Observational.

View on ClinicalTrials.gov
NCT05622929Completed

SAPPHIRE-LDL

1,465patients across 28 clinics

Digital intervention for LDL control. Cluster randomized trial.

View on ClinicalTrials.gov
NCT05285085Completed

RWE-Statins

2.1 millionparticipants (2,133,900)

Real-world evidence on statin use in Brazil.

View on ClinicalTrials.gov
Studies approved by the CEP/CONEP system (5)
epCertify HiperdiaHypertension and diabetes · Hospital Moinhos de Vento16/12/2025
COVID-19 ACS BrasilRespiratory symptom screening by community health workers · Hospital Israelita Albert Einstein28/09/2022
AVC ACS BrasilProfile of stroke patients and access to rehabilitation in the Family Health Strategy · Hospital Israelita Albert Einstein23/05/2022
ICHealthProfile of heart failure patients cared for by the Family Health Strategy13/10/2020
DPOC ACS BrasilProfile of COPD patients cared for by the Family Health Strategy · Hospital Israelita Albert Einstein30/04/2020

Approval can be verified at plataformabrasil.saude.gov.br (Público › Confirmar aprovação, using the CAAE or opinion number).

Primary Care Insights

Brazilian primary care, in national overviews

National reports built from public SUS data — from viral hepatitis testing to 12 years of primary care output.

Viral hepatitis in primary carePrimary care in data
International presence

Where we have presented our results

epHealth presentation at the University of Cambridge
United Kingdom

University of Cambridge

Presentation at the European Society of Cardiology Congress
Paris, France

European Society of Cardiology Congress

Presentation at the FutureHub of the American College of Cardiology Scientific Session
New Orleans, USA

American College of Cardiology Scientific Session

FAQ

Frequently asked questions

What is real-world evidence?

It comes from studies that use everyday care data — such as primary care records — rather than controlled settings alone. It helps support public policy, clinical decisions and health strategies.

Are the studies reviewed by an ethics committee?

Yes. Our studies are approved by Brazil's CEP/CONEP system, and our clinical trials are registered on ClinicalTrials.gov.

What is APS Play?

It is the continuing education platform for primary care professionals: short courses with video lessons, support materials and a certificate at the end, designed for mobile.

What is the difference between epHealth and Instituto epHealth?

epHealth is the technology and research company. Instituto epHealth is the nonprofit organization that works in public health.

How do I start a project with epHealth?

Write to us using the form below or at info@ephealth.com.br. Our team replies within 2 business days.

Contact us

Let's talk about your next study

Tell us what you need. Our research, technology and public health team replies within 2 business days.

info@ephealth.com.br +55 (48) 93618-2615 Florianópolis — SC, Brazil

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